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NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional)

by National Institutes of Health

NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional), run by National Institutes of Health, offers non-dilutive federal R&D funding for small businesses. Applications close Apr 5, 2029 · time not confirmed.

Benefits

Non-dilutive federal R&D funding for small businesses

Eligibility

Only United States small business concerns (SBCs) that have previously received an NIH SBIR or STTR Phase II award are eligible to submit applications for this opportunity. Only one NIH Phase IIB Strategic Breakthrough award is allowed per project.

Open to: United States

Timeline

Opens
May 28, 2026
Deadline
Apr 5, 2029 · time not confirmed
Recurring
Annual · next expected May 28, 2027
Fee
None

The organizer doesn’t state a time; OSH treats the deadline as the end of that day anywhere on Earth.

Questions and answers

When is the deadline for NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional)?

The deadline is Apr 5, 2029 · time not confirmed. The organizer does not state a time, so OSH treats it as the end of that day anywhere on Earth.

Who can apply to NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional)?

Only United States small business concerns (SBCs) that have previously received an NIH SBIR or STTR Phase II award are eligible to submit applications for this opportunity. Only one NIH Phase IIB Strategic Breakthrough award is allowed per project.

What does NIH Small Business Innovation Research (SBIR) Phase IIB Strategic Breakthrough Award (Parent [R44] Clinical Trial Optional) offer?

Non-dilutive federal R&D funding for small businesses.

Is there an application fee?

None

Sources

  1. 1.Grants.gov — May 28, 2026 · Official

Verified by OSH — Confirmed by at least two independent sources or a primary document (filing, official announcement).Last verified Nov 3, 2026